Clinical development failure
Drug candidates may not demonstrate acceptable efficacy, safety, or tolerability.
- Scope
- TERN-701, TERN-501, TERN-800 series
- Materiality
- high
Terns Pharmaceuticals, Inc. is a U.S.-based clinical-stage biopharmaceutical company focused on discovering and developing small-molecule medicines for oncology and metabolic diseases. Its pipeline includes internally discovered drug candidates such as TERN-701 and TERN-501, along with the TERN-800 series of GIPR modulators for obesity.
62.41
62.41
| % | |
|---|---|
| Oncology pipeline | 0% Small-molecule drug candidates for cancer treatment, including TERN-701 and TERN-501. |
| Metabolic disease pipeline | 0% Obesity-focused programs built around GIPR modulation and combination approaches. |
| Discovery and preclinical development | 0% Internal discovery, preclinical research, and candidate nomination activities. |
| Clinical development | 0% Human clinical testing and related regulatory development for pipeline assets. |
| Out-licensing and partnering | 0% Potential milestone-based collaboration and license arrangements for select programs. |
Terns does not sell commercial products; its direct counterparties are primarily pharmaceutical partners, contract...
Potential licensees or collaborators that may fund or regionalize development of TERN-701 or metabolic assets.
Service providers that support discovery, manufacturing, and clinical execution.
FDA and foreign regulators that review INDs, trial plans, and marketing applications.
Patients who would ultimately receive TERN-701 or related oncology therapies if approved.
Patients who would ultimately receive GIPR-based metabolic therapies if approved.
Terns is headquartered in the United States, but its development footprint is international because clinical trials,...
Terns is prioritizing advancement of its oncology lead program, especially TERN-701, while maintaining a selective...
The company views this as its most important internal program and a key value driver.
Partnerships can provide external funding, regional reach, and development support.
GIPR modulation may create combination opportunities with GLP-1 therapies.
Terns faces the typical risks of a clinical-stage biotech company: clinical failure, regulatory delay, and dependence...
Drug candidates may not demonstrate acceptable efficacy, safety, or tolerability.
FDA and foreign agency disruptions can slow guidance, review, and approvals.
Manufacturers, suppliers, and trial activity in China can be affected by tariffs, sanctions, or export restrictions.
The company has no product revenue and relies on external financing to fund development.
Potential collaborators may demand favorable economics or decline to partner if competing assets look stronger.
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: 29/04/2026