CYRXNasdaqPharmaceutical PreparationsUS GAAP · USD

Cryoport, Inc.

Cryoport, Inc. provides temperature-controlled supply chain solutions for the life sciences industry, with a particular focus on cell and gene therapies. The company combines logistics, biostorage, bioservices, cryopreservation, and cryogenic equipment manufacturing to help customers move and store sensitive biological materials under tightly regulated conditions.

Revenue176m USD
Operating profit (EBIT)-36.8m USD
+71.9 %y/y
EBIT margin-20.9%
Net income78.3m USD
+168.2 %y/y
Free cash flow-25.0m USD
+25.5 %y/y

Fiscal year 2025 · change from previous year

Development 2020–2025

-200-1000100200300m USD2020: 79 m USD2020: EBIT -30 m USD20202021: 223 m USD2021: EBIT -18 m USD20212022: 237 m USD2022: EBIT -32 m USD20222023: 233 m USD2023: EBIT -101 m USD20232024: EBIT -131 m USD20242025: 176 m USD2025: EBIT -37 m USD2025176-37
RevenueOperating profit (EBIT)

Business

Share of revenue
Life Sciences Services55 %

Temperature-controlled logistics, biostorage, bioservices, and cryopreservation for life science customers.

Life Sciences Products45 %

Cryogenic systems such as freezers, dewars, and related accessories sold directly or through distributors.

Products

Reported · share of revenue
45.2%44.4%10.4%FY2025100 %
  • Products45.2 %
  • Biologistics Solutions44.4 %
  • Biostorage Bioservices10.4 %

Source: 10-K FY2025, revenue the company reports per product line (SEC XBRL). Shares are of the lines shown and add up to 100 %.

Customers

Cryoport sells primarily to life sciences customers that need validated, compliant handling of sensitive biological materials. Its customer base includes biotech and pharmaceutical companies, CROs, CDMOs, central laboratories, fertility clinics, animal health companies, universities, and research facilities, with especially strong exposure to cell and gene therapy programs.

Biotechnology and pharmaceutical companies

Buy logistics, storage, and cryopreservation services for clinical and commercial biologics, especially CGT programs.

Contract research organizations and CDMOs

Use Cryoport to move trial materials and support outsourced development/manufacturing workflows.

Clinical trial sponsors

Need compliant, traceable transport for patient- or donor-derived materials across global trials.

Fertility and reproductive medicine providers

Buy cryopreservation and temperature-controlled handling for reproductive materials.

Animal health and research institutions

Purchase cryogenic systems and logistics for biological samples and research materials.

Strategy

Cryoport is focused on deepening its position in cell and gene therapy supply chains by combining digital logistics, compliance, and global infrastructure. Management is also investing in technology, geographic expansion, and new supply chain initiatives while using the CRYOPDP divestiture and DHL partnership to sharpen its international operating model.

Grow in cell and gene therapy supply chainsMedium term

CGT programs require specialized, validated logistics and create sticky customer relationships.

Digitize and integrate the operating platformMedium term

A unified digital layer improves visibility, compliance, and execution across global shipments and storage.

Rebalance the international network after CRYOPDP divestitureShort term

The divestiture frees capital and allows focus on higher-value services and strategic partnerships.

Geography

Q1/2026

Cryoport generates most of its revenue in the Americas, with meaningful exposure to EMEA and APAC. The company operates globally and uses its international footprint to support regulated life sciences supply chains, while foreign exchange and local compliance requirements affect execution and margins.

Americas73 %
Europe, Middle East and Africa19 %
Asia Pacific8.1 %

Share of the revenue the company reports by geography.

Risks

Cryoport faces execution risk from its dependence on regulated life sciences demand, especially CGT programs that can be delayed by funding or clinical setbacks. International exposure adds FX, trade, and geopolitical risk, while the company also remains vulnerable to customer concentration, government funding disruptions, and the need to keep investing before reaching sustained profitability.

Sorted by severity
LowMediumHighLowMediumHighImpact →Likelihood →Need for continued external capital1Foreign currency and international operating risk3U.S. federal funding disruption4
Impact is the risk’s severity and likelihood how probable it is over the next few years, both assessed from the company’s reports. Numbers match the list.
  1. Need for continued external capitalImpact: HighLikelihood: High

    The company expects near-term operating losses while investing in growth, which may require equity or debt financing.

    Exposure: Liquidity and acquisition capacity

  2. Dependence on cell and gene therapy program activityImpact: High

    Clinical and commercial programs can be delayed, canceled, or scaled back, reducing demand for specialized logistics and storage.

    Exposure: BioLogistics and BioStorage demand

  3. Foreign currency and international operating riskImpact: MediumLikelihood: Medium

    Revenue and costs in Europe and Asia are exposed to exchange-rate swings, local regulation, and geopolitical disruption.

    Exposure: EMEA and APAC operations

  4. U.S. federal funding disruptionImpact: MediumLikelihood: Medium

    Some customers rely on federal funding or agency oversight, and shutdowns can delay purchasing decisions.

    Exposure: U.S. customer base

  5. Customer concentrationImpact: Medium

    A single customer represented 10.2% of total revenue in 2025, which can create volatility if volumes change.

    Exposure: Life Sciences Services segment

Accounting

Judgemental items
Revenue recognition timing

Revenue is recognized upon delivery or when control transfers, so shipping cutoffs and customer-arranged couriers affect period results.

Impact: Quarterly revenue comparability

Discontinued operations

The CRYOPDP divestiture is reported separately, which changes trend analysis for continuing operations.

Impact: Segment and consolidated comparability

Goodwill impairment

The company recorded prior impairments in the MVE reporting unit and still tests goodwill annually.

Impact: Non-cash earnings volatility

Contingent consideration and fair value estimates

Changes in fair value can materially affect operating results and require judgment.

Impact: Reported earnings and balance sheet values

Publicly listed companies with a comparable business focus.

Last updated: 24/09/2026

Cryoport, Inc. (CYRX) Revenue, Earnings & Financials 2025 – Clarifo