Sol-Gel Technologies Ltd.
Sol-Gel Technologies Ltd. is an Israel-based dermatology and pharmaceutical company that develops and commercializes prescription treatments for skin diseases. Its business centers on branded topical products and product candidates, with commercialization carried out directly in some markets and through licensing partners in others.
Tilikausi 2025 · muutos edellisvuodesta
Kehitys 2020–2025
Liiketoiminta
Osuus liikevaihdostaApproved prescription skin treatments sold through partners and licensees in multiple territories.
Investigational dermatology programs being advanced through clinical development.
Upfront, milestone, and royalty income from out-licensing commercial rights by territory.
Tuotteet
Raportoitu · osuus liikevaihdosta- License95,9 %
- Royalty3,6 %
- Services and other0,4 %
Lähde: 20-F FY2025, yhtiön tuotelinjoittain raportoima liikevaihto (SEC XBRL). Osuudet on laskettu näytetyistä riveistä ja ne summautuvat 100 %:iin.
Asiakkaat
Sol-Gel sells into the dermatology prescription market, so the end users are patients treated by dermatologists and other prescribing physicians. Its commercial counterparties are pharmaceutical partners and licensees that obtain rights to market TWYNEO® and EPSOLAY® in specific countries or regions. Revenue is therefore driven by both product demand in local markets and the pace of partner-led launches.
Dermatologists and other physicians prescribe TWYNEO® and EPSOLAY® for acne and rosacea.
Pharma partners buy commercialization rights, pay milestones, and generate royalties in their markets.
Patients are the end users of the prescription products, with demand driven by disease prevalence and physician adoption.
Sites and investigators support development of SGT-610 and other pipeline studies.
Strategia
Sol-Gel’s strategy is to expand TWYNEO® and EPSOLAY® through territory-by-territory licensing agreements that can generate upfront, milestone and ongoing royalty income. At the same time, it is advancing SGT-610 through clinical development to broaden the pipeline beyond marketed dermatology assets.
Broader territory coverage increases upfront payments, milestone potential and future royalties.
Royalties depend on partner commercialization and market launch timing.
Pipeline success could create a new future dermatology franchise beyond current products.
Maantiede
2025Sol-Gel is headquartered in Ness Ziona, Israel, and its commercial footprint spans a mix of direct and partner-led international markets. The company has signed licensing agreements covering parts of Europe, South Africa, South Korea, Australia and New Zealand, with additional rights in India, China, Hong Kong, Macau, Taiwan, Israel, and Canada. This geography mix makes the business dependent on partner execution and regulatory timing across multiple jurisdictions.
Osuus liikevaihdosta, jonka yhtiö raportoi maantieteellisesti.
Riskit
Sol-Gel depends on the success of clinical development, regulatory approvals, and partner commercialization, all of which can delay or prevent revenue generation. Because much of the business is licensed internationally, execution risk is shared with third parties and exposed to local market, regulatory and launch-timing uncertainty.
- Partner commercialization riskVaikutus: KorkeaTodennäköisyys: Korkea
Royalties and milestones depend on licensees successfully launching and marketing the products.
Kohdistuu - Clinical development risk for SGT-610Vaikutus: KorkeaTodennäköisyys: Kohtalainen
The product candidate must succeed in late-stage trials to support future value creation.
Kohdistuu: Phase 3 Gorlin syndrome program and HF-BCC study
- Regulatory approval and timing riskVaikutus: KorkeaTodennäköisyys: Kohtalainen
Commercialization depends on obtaining approvals and avoiding delays in target markets.
Kohdistuu: TWYNEO® and EPSOLAY® launches across multiple countries
- Geopolitical exposure in IsraelVaikutus: KeskitasoTodennäköisyys: Kohtalainen
The company is headquartered in Israel and referenced regional conflict as a business risk.
Kohdistuu: Corporate operations and oversight in Israel
Kirjanpito
Harkinnanvaraiset erätDifferent streams such as product sales, royalties and milestones may be recognized at different points in time.
Vaikutus: Can cause uneven quarterly revenue
R&D expenses are driven by trial phases, patient enrollment and external study costs.
Vaikutus: Affects operating loss and cash burn
The company holds marketable securities that can affect financial income and balance-sheet values.
Vaikutus: Impacts non-operating income
Biopharma companies often use equity awards to retain talent and fund operations.
Vaikutus: Affects operating expenses and equity
Samankaltaisia listattuja yhtiöitä
Julkisesti listattuja yhtiöitä, joilla on samankaltainen liiketoiminta.
Soligenix, Inc
SNGX · Pharmaceutical Preparations
Compugen Ltd
CGEN · Biological Products, (No Diagnostic Substances)
Evogene Ltd.
EVGN · Agricultural Chemicals
Soleno Therapeutics Inc
Pharmaceutical Preparations
Krystal Biotech, Inc.
KRYS · Biological Products, (No Diagnostic Substances)
Krystal Biotech is a commercial-stage biotechnology company that develops and sells genetic medicines built on an engineered HSV-1 gene therapy platform.
Biofrontera Inc.
BFRI · Pharmaceutical Preparations
Päivitetty: 28.9.2026