PACBNasdaqLaboratory Analytical InstrumentsUS GAAP · USD

Pacific Biosciences of California, Inc

Pacific Biosciences of California is a U.S.-based life science technology company that designs, develops, and manufactures DNA sequencing systems and consumables. Its core platform is HiFi long-read sequencing, used to generate highly accurate views of genomes, transcriptomes, and epigenomes for research and clinical applications.

Liikevaihto160milj. USD
Liikevoitto (EBIT)−554milj. USD
−16,8 %v/v
EBIT-marginaali−346,2%
Nettotulos−546milj. USD
−76,3 %v/v
Vapaa kassavirta−114milj. USD
+46,3 %v/v

Tilikausi 2025 · muutos edellisvuodesta

Kehitys 2020–2025

−600−400−2000200milj. USD2020: EBIT −104 milj. USD20202021: EBIT −210 milj. USD20212022: EBIT −307 milj. USD20222023: EBIT −334 milj. USD20232024: EBIT −474 milj. USD20242025: 160 milj. USD2025: EBIT −554 milj. USD2025160−554
LiikevaihtoLiikevoitto (EBIT)

Liiketoiminta

Osuus liikevaihdosta
Instruments34 %

Sequencing platforms sold to laboratories for genome analysis and related applications.

Consumables51 %

Reagents and other recurring-use materials consumed on installed sequencing systems.

Service and other15 %

Maintenance agreements, support, and other service-related revenue.

Tuotteet

Raportoitu · osuus liikevaihdosta
51,2%33,6%15,2%FY2025100 %
  • Consumable51,2 %
  • Instrument33,6 %
  • Service and Other15,2 %

Lähde: 10-K FY2025, yhtiön tuotelinjoittain raportoima liikevaihto (SEC XBRL). Osuudet on laskettu näytetyistä riveistä ja ne summautuvat 100 %:iin.

Asiakkaat

PacBio sells to research and clinical laboratories that need long-read sequencing for complex genomic analysis. Its customer base includes academic and government institutions, genome centers, hospitals, CROs, pharmaceutical companies, agricultural companies, and commercial testing labs. Many customers buy instruments first and then generate recurring consumables demand as they run samples over time.

Academic and government research

Buy sequencing systems and consumables for basic and translational genomics research.

Clinical and hospital labs

Use HiFi sequencing for rare disease, inherited disease, oncology, and clinical research.

Commercial testing and service labs

Purchase systems to sequence samples for third parties and generate service revenue.

Pharmaceutical and CRO customers

Use the platform for drug discovery, biomarker work, and complex genomic workflows.

Agricultural and applied science customers

Use long-read sequencing for plant and animal science applications.

Strategia

PacBio’s strategy centers on expanding adoption of HiFi long-read sequencing across research and clinical use cases. It aims to improve throughput, simplify workflows, lower sequencing cost, and broaden the installed base so consumables revenue grows with instrument placements. The company also relies on partnerships and third-party tools to strengthen sample preparation, informatics, and market reach.

Drive platform adoptionKeskipitkä aikaväli

Instrument placements create recurring consumables demand and deepen customer relationships.

Broaden applicationsKeskipitkä aikaväli

More use cases increase the addressable market and reduce dependence on a narrow set of buyers.

Strengthen commercial executionLyhyt aikaväli

A specialized sales and support model is needed to convert scientific interest into placements.

Maantiede

Q1/2026

PacBio is headquartered in the United States and sells through a global direct sales force plus distribution partners. The company serves customers across North America, Europe, the Middle East, Africa, Asia, Australia, and the Americas, which makes international adoption and export access important to growth. Its operating footprint and partner network matter because sequencing systems are sold into specialized research and clinical markets that are concentrated in major scientific hubs.

Americas45 %
EMEA29 %
Asia Pacific26 %

Osuus liikevaihdosta, jonka yhtiö raportoi maantieteellisesti.

Riskit

PacBio faces intense competition from larger and better-resourced sequencing companies, which can pressure pricing and slow adoption. Its business also depends on customer acceptance of new platforms, third-party sample prep and informatics tools, and continued access to international markets; large customer orders can create quarter-to-quarter volatility. Because the company has historically operated at a loss and may need external capital, execution and funding risk remain important.

Järjestetty vakavuuden mukaan
MatalaKohtalainenKorkeaMatalaKohtalainenKorkeaVaikutus →Todennäköisyys →Competitive pressure in nucleic acid sequencing1Customer concentration and order timing2Capital needs and operating losses3Product adoption and ecosystem dependence4Export and regulatory restrictions5
Vaikutus on riskin vakavuus ja todennäköisyys sen toteutumisen todennäköisyys lähivuosina, molemmat arvioitu yhtiön raporttien perusteella. Numerot vastaavat listaa.
  1. Competitive pressure in nucleic acid sequencingVaikutus: KorkeaTodennäköisyys: Korkea

    Rivals may have greater resources, broader installed bases, and faster product development.

    Kohdistuu: Instrument and consumables sales

  2. Customer concentration and order timingVaikutus: KorkeaTodennäköisyys: Korkea

    A limited number of large purchase orders can cause material revenue volatility.

    Kohdistuu: Quarterly revenue and forecasting

  3. Capital needs and operating lossesVaikutus: KorkeaTodennäköisyys: Korkea

    The company has historically generated negative operating cash flow and may need external funding.

    Kohdistuu: Liquidity and strategic execution

  4. Product adoption and ecosystem dependenceVaikutus: KeskitasoTodennäköisyys: Kohtalainen

    Demand depends on third-party sample prep and informatics tools that may be delayed or unavailable.

    Kohdistuu: Market acceptance of HiFi platforms

  5. Export and regulatory restrictionsVaikutus: KeskitasoTodennäköisyys: Kohtalainen

    Future U.S. export controls could limit sales to certain countries or applications.

    Kohdistuu: International revenue

Kysy Clarifolta: Pacific Biosciences of California, Inc

Kirjanpito

Harkinnanvaraiset erät
Revenue recognition by product line

Instruments are typically recognized at sale, while consumables and service revenue recur over time.

Vaikutus: Affects revenue timing and mix

Quarterly volatility from large orders

Customer purchase timing can shift revenue between periods.

Vaikutus: Affects comparability and forecasting

Inventory reserves and warranty estimates

Sequencing systems and reagents require judgment on obsolescence and support obligations.

Vaikutus: Affects gross margin and operating results

Intangible asset and impairment testing

Acquired technologies and other long-lived assets require periodic valuation assessments.

Vaikutus: Can create non-cash charges

Julkisesti listattuja yhtiöitä, joilla on samankaltainen liiketoiminta.

Päivitetty: 24.9.2026

Pacific Biosciences of California, Inc (Nasdaq) – Laboratory Analytical Instruments | Analyysi – Clarifo