Clinical development failure
Lead programs may not demonstrate sufficient safety or efficacy in trials.
- Scope
- ORIC-944, ORIC-114, ORIC-533
- Materiality
- high
ORIC Pharmaceuticals is a U.S.-based clinical-stage biopharmaceutical company focused on discovering and developing cancer therapies designed to overcome treatment resistance. Its pipeline centers on oncology programs in hormone-dependent cancers, precision oncology, and key tumor dependencies, with development activities run from its South San Francisco headquarters.
14.13
14.13
| % | |
|---|---|
| Clinical-stage oncology programs | 100% Investigational drug candidates in human clinical trials for cancer. |
| Preclinical discovery pipeline | 0% Earlier-stage internal and in-licensed programs aimed at resistance mechanisms. |
ORIC does not sell commercial products today; its direct counterparties are clinical trial sites, research...
Hospitals, investigators, and research networks that enroll patients and run ORIC-sponsored studies.
Companies such as Johnson & Johnson and Bayer that supply combination agents and support studies.
Owners of external programs that ORIC in-licenses to expand its pipeline.
Patients with resistant cancers who would use ORIC therapies if approved.
ORIC is headquartered in South San Francisco, California and operates as a U.S.-based development company...
ORIC’s strategy is to concentrate resources on a small number of differentiated oncology assets, especially ORIC-944...
This is a lead asset in resistant prostate cancer and a core value driver.
It broadens the pipeline beyond hormone-dependent cancers and targets resistant mutations.
External innovation can add assets without relying only on internal discovery.
ORIC is a clinical-stage company with no commercial revenue, so its value depends heavily on successful clinical...
Lead programs may not demonstrate sufficient safety or efficacy in trials.
The company has no revenue and must fund long development timelines.
Trials, manufacturing, and combination studies depend on external partners and suppliers.
Large oncology companies can move faster, fund more studies, and reach patients sooner.
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: 29/04/2026