SYNACTNasdaq StockholmHealth CareIFRS · SEK

SynAct Pharma

SynAct Pharma AB is a clinical stage biotechnology company based in Lund, Sweden, specializing in the resolution of inflammation through the selective activation of the melanocortin system. The company develops a portfolio of oral and injectable selective melanocortin agonists aimed at treating autoimmune and inflammatory diseases. SynAct Pharma's business model focuses on advancing projects to clinical proof-of-concept, specifically targeting Phase 2 studies, before entering commercial agreements with major pharmaceutical companies. The company is listed on Nasdaq Stockholm and operates through its subsidiaries in Denmark and Switzerland.

Operating profit (EBIT)-90.0m SEK
+0.0 %y/y
Net income-111m SEK
−34.5 %y/y

Fiscal year 2025 · change from previous year

Development 2021–2025

-250-200-150-100-500m SEK2021: 0.00 m SEK2021: EBIT -77 m SEK20212022: 0.00 m SEK2022: EBIT -106 m SEK20222023: 0.00 m SEK2023: EBIT -224 m SEK20232024: 0.00 m SEK2024: EBIT -90 m SEK20242025: EBIT -90 m SEK2025-90
RevenueOperating profit (EBIT)

Business

Share of revenue
Melanocortin Agonists50 %

Includes oral and injectable compounds for inflammation resolution.

Clinical Development30 %

Services related to advancing clinical trials to Phase 2.

Research Collaborations20 %

Collaborative projects with research institutions.

Customers

SynAct Pharma primarily targets pharmaceutical companies interested in innovative treatments for autoimmune and inflammatory diseases. Their customer base includes large pharmaceutical firms looking to license new therapies after proof-of-concept is established. Additionally, they collaborate with research institutions for the development of new drug candidates. The company's focus on non-suppressive therapies appeals to companies seeking alternatives to traditional immune-suppressive treatments.

Pharmaceutical Companies

They license therapies post proof-of-concept for autoimmune diseases.

Research Institutions

Collaborate on developing new drug candidates.

Biotech Firms

Interested in non-suppressive inflammation therapies.

Strategy

SynAct Pharma's strategic priorities include advancing its lead compound, resomelagon, through Phase 2 clinical trials and securing strategic partnerships with major pharmaceutical companies. The company aims to expand its therapeutic applications to include acute inflammation due to viral infections. By focusing on non-suppressive therapies, SynAct Pharma seeks to differentiate itself in the competitive biotech landscape. The company is also exploring opportunities for geographic expansion to enhance its market reach.

Advance resomelagon in clinical trialsMedium term

To establish proof-of-concept and attract partners.

Expand therapeutic applicationsLong term

To address larger markets such as viral infections.

Secure strategic partnershipsShort term

To facilitate commercialization and market entry.

Geography

SynAct Pharma is headquartered in Lund, Sweden, and operates through subsidiaries in Denmark and Switzerland. The company is listed on Nasdaq Stockholm, providing it with a strong presence in the European market. Its strategic location in Scandinavia allows for collaboration with leading research institutions across Europe. The company's geographic focus supports its business model by facilitating access to European regulatory bodies and potential partners.

Risks

Key risks for SynAct Pharma include the inherent uncertainties of drug development, such as clinical trial outcomes and regulatory approvals. The company also faces competition from other biotech firms developing similar therapies. Financial risks include the need for continuous funding to support R&D activities. Additionally, currency fluctuations and changes in regulatory requirements could impact operations. The company's reliance on partnerships for commercialization poses a strategic risk if suitable partners are not secured.

Sorted by severity
LowMediumHighLowMediumHighImpact →Likelihood →Clinical trial outcomes1Regulatory approval3Competition4Funding requirements2
Impact is the risk’s severity and likelihood how probable it is over the next few years, both assessed from the company’s reports. Numbers match the list.
  1. Clinical trial outcomesImpact: CriticalLikelihood: Medium

    Uncertainty in achieving desired results.

  2. Funding requirementsImpact: HighLikelihood: High

    Need for continuous investment in R&D.

  3. Regulatory approvalImpact: HighLikelihood: Medium

    Complex and evolving requirements.

  4. CompetitionImpact: HighLikelihood: Medium

    Other firms developing similar therapies.

Accounting

Judgemental items
R&D expense recognition

Impacts financial results and projections.

Intangible asset valuation

Affects balance sheet and financial health.

Revenue recognition timing

Crucial for financial projections and reporting.

Publicly listed companies with a comparable business focus.

Last updated: 24/09/2026