ZYBTNasdaqPharmaceutical PreparationsUS GAAP · USD

Zhengye Biotechnology Holding Ltd

Zhengye Biotechnology Holding Ltd is a Cayman Islands holding company with operating activities centered in Jilin, China through its veterinary vaccine business. The company develops, manufactures, and sells veterinary vaccines, with a particular focus on livestock vaccines in China.

Revenue116m USD
−37.6 %y/y
Operating profit (EBIT)-70.5m USD
−528.9 %y/y
EBIT margin-60.6%
−69.4 ppy/y
Net income-69.8m USD
−717.0 %y/y
Free cash flow12.3m USD
−55.1 %y/y

Fiscal year 2025 · change from previous year

Development 2022–2025

-1000100200300m USD2022: 260 m USD2022: EBIT 66 m USD20222023: 212 m USD2023: EBIT 45 m USD20232024: 186 m USD2024: EBIT 16 m USD20242025: 116 m USD2025: EBIT -71 m USD2025116-71
RevenueOperating profit (EBIT)

Business

Share of revenue
Veterinary vaccines85 %

Vaccines designed to prevent disease in livestock and other farm animals.

R&D and formulation services10 %

Internal research, strain development, and vaccine formulation supporting product commercialization.

Manufacturing services5 %

Production and packaging of veterinary biologics at the company's facilities in China.

Products

Reported · share of revenue
52.9%44.6%FY2025100 %
  • Distribution Network52.9 %
  • Direct Sales Channel44.6 %
  • Government Tender and Procurement2.5 %

Source: 20-F FY2025, revenue the company reports per product line (SEC XBRL). Shares are of the lines shown and add up to 100 %.

Customers

The company sells primarily to livestock-focused animal health customers in China, where vaccine purchasing is tied to herd health management and disease prevention. Its buyers are typically organizations that need consistent supply of veterinary biologics for farm and production-animal use. Demand is driven by the need to protect animal populations, reduce mortality, and support productivity in livestock operations.

Livestock farms

Buy veterinary vaccines for herd disease prevention and productivity protection.

Animal health distributors

Purchase products for resale into veterinary and agricultural channels.

Veterinary end users

Use vaccines in treatment and prevention protocols for farm animals.

Strategy

The company’s strategy is centered on building a veterinary vaccine platform spanning research, manufacturing, and sales. Its competitive position depends on maintaining product development capabilities and serving livestock health needs in China, where disease prevention is operationally important for producers. As a Nasdaq-listed Chinese operating company, it also depends on continued access to public capital markets and regulatory compliance.

Strengthen veterinary vaccine pipelineMedium term

New and improved vaccines support customer retention and product relevance.

Scale manufacturing and commercial executionMedium term

Integrated production and sales are necessary to meet farm and distributor demand.

Maintain public-market complianceShort term

U.S. listing status supports access to capital and investor visibility.

Geography

The business is operationally centered in Jilin, China, where the company’s principal executive office and operating base are located. Its commercial focus is China, particularly livestock vaccine demand, while the company is incorporated in the Cayman Islands and listed on Nasdaq in the United States. Geography matters because manufacturing, regulatory oversight, and end-market demand are concentrated in China even though the capital markets presence is offshore.

Risks

The company is exposed to demand fluctuations in livestock health markets, regulatory requirements for veterinary biologics, and execution risks in manufacturing and product quality. As a China-centered operating business with a U.S. listing, it also faces cross-border compliance, disclosure, and market volatility risks that can affect investor confidence and access to capital.

Sorted by severity
LowMediumHighLowMediumHighImpact →Likelihood →Livestock disease and demand variability1Manufacturing quality and product compliance2China concentration3Nasdaq listing and trading volatility4
Impact is the risk’s severity and likelihood how probable it is over the next few years, both assessed from the company’s reports. Numbers match the list.
  1. Livestock disease and demand variabilityImpact: HighLikelihood: Medium

    Vaccine demand depends on animal health conditions and farm purchasing cycles.

    Exposure: China livestock vaccine market

  2. Manufacturing quality and product complianceImpact: HighLikelihood: Medium

    Veterinary vaccines require strict production standards and regulatory oversight.

    Exposure: Vaccine manufacturing and sales

  3. China concentrationImpact: MediumLikelihood: High

    Commercial activities are focused in one country, increasing policy and market dependence.

    Exposure: Operations and end-market concentration

  4. Nasdaq listing and trading volatilityImpact: MediumLikelihood: Medium

    Share-price volatility can affect compliance status and investor perception.

    Exposure: Public listing in the United States

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Accounting

Judgemental items
Revenue recognition for product sales

Vaccine sales are typically recognized when control transfers, which depends on delivery terms.

Impact: Affects reported revenue timing and quarterly comparability

Inventory valuation

Biological products may face expiry, slow movement, or write-down risk.

Impact: Affects cost of sales and gross margin

Manufacturing overhead allocation

Production cost allocation can materially change unit costs for vaccine products.

Impact: Affects gross profit and inventory carrying values

Impairment of long-lived assets

Manufacturing assets and facilities may require impairment testing if utilization changes.

Impact: Affects operating results and asset values

Publicly listed companies with a comparable business focus.

Last updated: 28/09/2026

Zhengye Biotechnology Holding Ltd (Nasdaq) – Pharmaceutical Preparations | Financial Analysis – Clarifo